Breakpoints are from human CLSI M62 (2018), except where otherwise stated
1: Rapidly growing Mycobacteria include M smegmatis, fortuitum, chelonae, abscessus, phlei, thermoresistable
2: Mycobacterium avium complex include M avium, intracellulare
3: Other slow growing Mycobacteria include M genavense, terrae, xenopi, ulcerans, marinum
4: Clarithromycin susceptibility is used as surrogate for azithromycin
5: Ciprofloxacin susceptibility may be used as surrogate for veterinary marbofloxacin
6: Moxifloxacin susceptibility may be used as surrogate for veterinary pradofloxacin
7, 8: Doxycycline and minocycline human breakpoints may not be directly transferrable to animal isolates due to differences in drug absorption, distribution, metabolism and excretion. CLSI VET08 (2018) breakpoints for canine Staphylococcus pseudintermedius Doxycycline ≤ 0.125 -- 0.25 -- ≥ 0.5 Minocycline ≤ 0.5 -- 1 -- ≥ 2
